While the importance of ligand-receptor binding kinetics on drug action is becoming well established, focus to date has been almost entirely on the role of the dissociation constant on drug efficacy ...

THERE are difficulties in defining rate constants for the reactions of solids 1. Since a rate constant describes a rate it must have the dimension (time) −1. Constants with other dimensions with ...

In 1994, I was a second year Ph.D. student, and when searching for the values of the rate constants of actin filament assembly, I came across a 1986 paper by Tom Pollard, which had a huge impact on my ...